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KMID : 1189420070200020102
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2007 Volume.20 No. 2 p.102 ~ p.107
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The Experimental Study of Yeouigeumhwang-san on Antioxidant Effects
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Yoo Jin-Gon
Seo Hyeong-Sik
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Abstract
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Objectives: This experiment study was performed to investigate the antioxidant effects of Yeouigeumhwang-san(YUGHS).
Methods: Antioxidant effects of YUGHS on HaCaT cell, that were measured by the scavenging for DPPH radical, the formation of intracellular GSH and the inhibition for ROS.
Results: 1. YUGHS showed an oxidation inhibitory effect by decreasing the DPPH radicals. 2. Concentrations of 20 ug/ml, 50 ug/ml YUGHS slightly increased the formation of intracellular GSH in HaCaT cell. 3. Concentration of 50 ug/ml YUGHS slightly inhibited the production of ROS in the HaCaT cell stimulated with , but it is not significant.
Conclusions: These results indicate that YUGHS has antioxidant effects. If further study is performed, the use of YUGHS will be valuable and benificial in the therapy of inflammation.
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KEYWORD
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Yeouigeumhwang-san, YUGHS, Antioxidanteffects, DPPH, GSH, ROS
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